Jo Bristow, a health service administrator from Watton, is tackling the London Marathon as part of the Mr Men and Little Miss team, supporting the charity Children with Leukaemia.

Jo Bristow, a health service administrator from Watton, is tackling the London Marathon as part of the Mr Men and Little Miss team, supporting the charity Children with Leukaemia.

Jo, who will be 45 for next month's run, chose the charity in memory of her sister who died last year. It is her first marathon and she is hoping to raise as much as possible.

Mr Men and Little Miss team is easy to spot with runners donning Mr Happy and Mr Tickle running vests. Leukaemia is the most common form of childhood cancer, with children under five accounting for half of all cases.

Children with Leukaemia was set up by Eddie and Marion O'Gorman family after the death of their son Paul, aged 14. Just nine months later they lost their daughter Jean to cancer. It is dedicated exclusively to the conquest of childhood leukaemia through pioneering research, new treatment and support of leukaemic children and their families.